一、基本情况介绍
蒋文洁，女，博士，副教授，微生物与生化药学硕士研究生导师。
联系方式：E-mail：w.jiang@sdu.edu.cn；电话：0531-88382235。地址：济南市文化西路44号 35222葡京集团，邮编250012。
二、工作和学习经历
2020.12至今，35222葡京集团，助理研究员、副教授
2018.08-2020.10，佛罗里达大学（University of Florida），博士后
2012.09-2017.12，35222葡京集团，微生物与生化药学，博士
2008.09-2012.06，35222葡京集团，药学，学士
三、研究方向
1.糖类免疫佐剂研究
2.糖疫苗
3.糖类抗肿瘤药物研发
四、承担科研项目
1.国家自然科学基金青年基金，82104049，2022.01-2024.12，主持。
2.国家重点研发计划子课题，2023YFA0914304-2，2023.12-2028.11，主持。
3.山东省自然科学基金青年基金，ZR2021QH252，2022.01-2024.12，主持。
4.山东省青年科技人才托举工程，SDAST2024QTA094，2024.10-2026.09，主持。
5.3522集团的新网站青年学者未来计划项目，2023.01-2027.12，主持。
五、教学工作
本科生课程：生物技术制药、生物技术制药实验。
研究生课程：生物药物学、生物分离技术、药学综合实验与实践。
六、代表性学术论文（#第一作者，*通讯作者）
1.Honglei Jiang, Shu Zhang, Yipan Chen, Fengshan Wang*,Wenjie Jiang*.Preparation and characterization of curdlan-chitosan conjugatenanoparticles asmucosal adjuvants for intranasal influenza H1N1 subunit vaccine,International Journal of Biological Macromolecules,2024, 266:131289.
2.Yipan Chen, Yan Wang, Zuyi Li, Honglei Jiang, Wei Pan, Minghui Liu,Wenjie Jiang,* Xinke Zhang*, Fengshan Wang*. Preparation and immunological activity evaluation of an intranasal protein subunit vaccine against ancestral and mutant SARS-CoV-2 with curdlan sulfate/O-linked quaternized chitosan nanoparticles as carrier and adjuvant,International Journal of Biological Macromolecules,2024, 276:133733.
3.Yipan Chen, Zuyi Li, Honglei Jiang, Longkun Wang, Yuhe Zhang, Xinke Zhang,Wenjie Jiang*, Fengshan Wang*. Biological evaluation of curdlan sulfate-based nanoparticles in trained immunity enhancement: In vitro and in vivo approaches,International Journal of Biological Macromolecules,2024, 281: 136208.
4.He Xiao, Ziqing Zeng,Wenjie Jiang*. Progresses in the study of polysaccharide from medicinal plants of the Asclepiadaceae family,Pharmaceutical Science Advances, 2024, 2: 100045.
5.Weilu Tian, Xinlei Song, Fengshan Wang*,Wenjie Jiang*. Study on the preparation and biological activities of low molecular weight squid ink polysaccharide from Sepiella maindroni,International Journal of Biological Macromolecules, 2023, 237:124040.
6.Lidan Wu, Na Zhao,Wenjie Jiang*, Fengshan Wang*. Effects of heparan sulfate from porcine mucosa on Aβ1–42-induced neurotoxicity in vitro and in vivo.International Journal of Biological Macromolecules, 2022, 206:823-836.
7.Na Zhao, Lidan Wu, Xinke Zhang,Wenjie Jiang*, Fengshan Wang*. Low molecular weight chondroitin sulfate ameliorates pathological changes in 5XFAD mice by improving various functions in the brain.Neuropharmacology, 2021, 199,108796.
8.Jiatong Guo#,Wenjie Jiang#, Qingjiang Li, Mohit Jaiswal, Zhongwu Guo. Comparative immunological studies of tumor-associated Lewis X, Lewis Y, and KH-1 antigens.Carbohydrate Research, 2020, 492, 107999.
9.Qingjiang Li#,Wenjie Jiang#, Jiatong Guo, Mohit Jaiswal, Zhongwu Guo. Synthesis of Lewis Y Analogues and Their Protein Conjugates for Structure−Immunogenicity Relationship Studies of Lewis Y Antigen.The Journal of Organic Chemistry, 2019, 84(21), 13232-41.
10.Wenjie Jiang, Yanna Cheng, Na Zhao, Lian Li, Yikang Shi, Aizhen Zong, Fengshan Wang, Sulfated polysaccharide of Sepiella Maindroni ink inhibits the migration, invasion and matrix metalloproteinase-2 expression through suppressing EGFR-mediated p38/MAPK and PI3K/Akt/mTOR signaling pathways in SKOV-3 cells.International Journal of Biological Macromolecules, 2018, 107:349-362.
11.Wenjie Jiang, Weilu Tian, Muhammad Ijaz, Fengshan Wang. Inhibition of EGF-induced migration and invasion by sulfated polysaccharide of Sepiella maindroni ink via the suppression of EGFR/Akt/p38 MAPK/MMP-2 signaling pathway in KB cells.Biomedicine & Pharmacotherapy, 2017, 95: 95-102.
